Doctor Strange is likely to gross more in its opening weekend than 2015's Ant-Man, industry experts say.
The super-hero film starring Benedict Cumberbatch opens in North America on the 4th November, and on Thursday a major tracking service projected a first weekend total of $64 million or higher.
This is a noticeable improvement on the debut of Marvel Studios most recent new franchise Ant-Man, which opened with $57 million in mid-July of last year.
The film sees Cumberbatch in the role of Stephen Strange, a former neurosurgeon who seeks the healing power of mystical figure The Ancient One, after a car accident leaves his hands seriously injured.
As the 14th feature film from juggernaut Marvel Studios, Doctor Strange is expected to become yet another franchise for their so-called 'Cinematic Universe' which also includes such characters as The Avengers and the Guardians of the Galaxy.
The film is directed by Scott Derrickson (Sinister) and also stars Tilda Swinton (The Lion, The Witch and the Wardrobe), Chiwetel Ejiofor (12 Years a Slave), and Mads Mikkelsen (Hannibal).